Zhu_2020_schizophrenia

Study: Metagenome-wide association of gut microbiome features for schizophrenia

Publication: Zhu et al., Metagenome-wide association of gut microbiome features for schizophrenia (2020, Nature Communications)

External link: SPIRE database (MAGs, genes and proteins including annotations)

Study accession: PRJEB29127

Last annotation change: 2025-09-29

Human Metadata

Active_social_avoidance

52%
4
 25
3
 23
1
 21
5
 11
other values
 10

Anxiety

52%
3
 31
1
 30
2
 14
4
 13
other values
 2

Blunted_affect

52%
4
 26
3
 24
1
 18
5
 11
other values
 11

Body_temperature_celsius

100%
36.5
 45
36.7
 22
36.3
 20
36.2
 16
other values
 68

Breathe_c_p_m

100%
20
 67
18
 48
19
 21
17
 14
other values
 21

Brief_Assessment_of_Cognition_in_schizophrenia_Symbol_Coding_BACS_SC

76%
38
 8
34
 7
46
 7
28
 6
other values
102

Brief_Visuospatial_Memory_TestRevised_BVMTR

76%
39
 7
40
 6
47
 6
34
 5
other values
106

Category_Fluency_Animal_Naming_Fluency

76%
47
 9
35
 6
36
 6
39
 6
other values
103

Conceptual_disorganization

52%
3
 27
1
 22
4
 15
2
 12
other values
 14

Delusions

52%
5
 36
4
 27
6
 9
1
 7
other values
 11

Depression

52%
1
 36
3
 30
2
 13
4
 10
5
 1

Diagnosis

100%
healthy
 81
first-episode
 49
relapse
 41

Diastolic_pressure_mmHg

100%
80
 50
70
 25
60
 8
74
 7
other values
 81

Difficulty_in_abstract_thinking

52%
3
 32
1
 16
2
 16
5
 12
other values
 14

Disorientation

52%
1
 59
3
 13
2
 12
4
 4
5
 2

Disturbance_of_volition

52%
1
 30
4
 22
3
 17
2
 12
other values
 9

Dopamine_ng_per_ml

90%
1.777368
 1
10.1186
 1
10.28022
 1
10.406898
 1
other values
151

Dwelling_condition

100%
famliy life
109
group living
 46
live alone
 16

Education_level

100%
college
 45
high school
 32
junior high school
 32
junior college
 24
other values
 38

Emotional_withdrawal

52%
4
 30
3
 16
1
 15
5
 15
other values
 14

Excitement

52%
1
 33
3
 27
2
 13
4
 12
5
 5

Frequency_of_drinking_yogurt_or_probiotic_drinks

100%
hardly
 84
often
 80
every day
 7

Frequency_of_eating_livestock_meat

100%
hardly
 81
twice or three times a week
 62
often
 28

Frequency_of_eating_nutrient_supplements

100%
hardly
153
twice or three times a week
 11
often
 7

Frequency_of_eating_poultry

100%
hardly
115
twice or three times a week
 40
often
 16

Frequency_of_eating_vegetables

100%
often
119
twice or three times a week
 43
hardly
 9

Gammaaminobutyric_acid_GABA_ng_per_L

90%
100.08463
 1
106.150368
 1
1063.851792
 1
108.648812
 1
other values
151

Glutamic_acid_muM

90%
10.014
 1
10.094
 1
10.197
 1
10.307
 1
other values
151

Grandiosity

52%
1
 57
3
 17
4
 9
2
 4
other values
 3

Guilt_feelings

52%
1
 37
3
 28
4
 13
2
 11
5
 1

Hallucinatory_behaviour

52%
5
 24
3
 18
1
 16
4
 16
other values
 16

Hopkins_Verbal_Learning_TestRevised_HVLTR

76%
43
 8
48
 7
37
 6
50
 6
other values
103

Hostility

52%
3
 34
1
 22
2
 14
4
 13
5
 7

In_the_past_six_months_exposure_to_secondhand_smoke_situation

100%
almost none
 74
less than 1 hour a day
 52
1 to 2 hours a day
 19
4 hours a day
 17
2 to 4 hours a day
 9

Kynurenic_acid_KYNA_nmol_per_L

90%
10.1757763363782
 1
10.2479397043897
 1
10.3119962784403
 1
10.3187362873213
 1
other values
151

Kynurenine_KYN_nmol_per_L

90%
912.566402
 2
1001.06351
 1
1122.583068
 1
1145.093782
 1
other values
149

Lack_of_judgment_and_insight

52%
6
 25
5
 25
4
 23
3
 16
7
 1

Lack_of_spontaneity

52%
4
 27
1
 19
3
 15
5
 15
other values
 14

Mannerism_and_posturing

52%
1
 42
3
 21
2
 20
4
 4
other values
 3

Marital_status

100%
single
102
married
 63
single after divorced
 6

MayerSaloveyCaruso_Emotional_Intelligence_Test_MSCEIT

73%
40
 8
27
 7
44
 7
37
 6
other values
98

Motor_retardation

52%
1
 25
3
 25
4
 19
2
 12
other values
 9

Neuropsychological_Assessment_Battery_NAB

76%
48
 7
41
 6
46
 6
49
 6
other values
105

Passive_or_apathetic_social_withdrawal

52%
4
 29
3
 24
5
 22
2
 6
other values
 9

Phenylalanine_muM

90%
62.88516254
 2
29.29959441
 1
30.3468733
 1
30.467946
 1
other values
150

Poor_attention

52%
3
 35
4
 30
1
 9
2
 9
other values
 7

Poor_impulse_control

52%
3
 33
1
 27
2
 14
4
 11
5
 5

Poor_rapport

52%
4
 25
3
 23
1
 18
2
 11
other values
 13

Preoccupation

52%
1
 24
4
 21
3
 19
2
 13
other values
 13

Pulse_c_p_m

100%
80
 22
75
 17
72
 15
78
 13
other values
104

Sample_center

100%
Xi'an
97
Lintong
 19
Weinan
 19
Hanzhong
 15
other values
 21

Serotonin_ng_per_ml

90%
1276.402
 2
2435.576
 2
3897.592
 2
4761.44
 2
other values
147

Smoking

100%
never smoke or occasional smoke
123
smoking more than 10 cigarettes day or quit smoking failed
 15
intermittent smoking
 15
smoking 5 to 10 cigarettes a day
 9
Smoking less than or equal to 4 cigarettes a day
 9

Somatic_concern

52%
1
 40
3
 26
2
 12
4
 10
5
 2

Staple_food_structure

100%
flour
86
rice
 53
rice,flour,coarse food grain
 27
coarse food grain
 5

Stereotyped_thinking

52%
1
 49
3
 22
2
 11
5
 6
4
 2

Suspiciousness_and_persecution

52%
5
 33
4
 19
1
 12
3
 12
other values
 14

Systolic_pressure_mmHg

100%
120
 41
110
 20
100
 11
117
 8
other values
91

Tension

52%
3
 44
1
 18
2
 16
4
 10
5
 2

Trail_Making_Test_TMT

76%
39
 7
27
 6
33
 6
35
 6
other values
105

Tryptophane_muM

90%
0.5741
 2
0.3525
 1
0.36
 1
0.3729
 1
other values
150

Tyrosine_muM

90%
41.79590485
 2
100.4139301
 1
150.7312766
 1
26.14382692
 1
other values
150

Uncooperativeness

52%
1
 34
3
 22
2
 20
4
 10
other values
 4

Unusual_thought_content

52%
1
 28
4
 23
3
 20
2
 10
5
 9

Wechsler_Memory_ScaleIII_WMS_III

76%
31
 9
37
 7
36
 6
39
 6
other values
102

follow_up_BGI_ID

 22%
wHAXPI037148-13
 1
wHAXPI037149-14
 1
wHAXPI037150-16
 1
wHAXPI037151-26
 1
other values
 34

follow_up_BMI

 22%
22.0385674931129
 2
23.4375
 2
15.625
 1
16.9370318792578
 1
other values
 32

follow_up_Brief_Assessment_of_Cognition_in_schizophrenia_Symbol_Coding_BACS_SC

76%
38
 8
34
 7
46
 7
28
 6
other values
102

follow_up_Brief_Visuospatial_Memory_TestRevised_BVMTR

76%
39
 7
40
 6
47
 6
34
 5
other values
106

follow_up_Category_Fluency_Animal_Naming_Fluency

76%
47
 9
35
 6
36
 6
39
 6
other values
103

follow_up_Drugs

 22%
risperidone, others
 20
others
 11
risperidone
 7

follow_up_Hopkins_Verbal_Learning_TestRevised_HVLTR

76%
43
 8
48
 7
37
 6
50
 6
other values
103

follow_up_MayerSaloveyCaruso_Emotional_Intelligence_Test_MSCEIT

73%
40
 8
27
 7
44
 7
37
 6
other values
98

follow_up_Neuropsychological_Assessment_Battery_NAB

76%
48
 7
41
 6
46
 6
49
 6
other values
105

follow_up_Trail_Making_Test_TMT

76%
39
 7
27
 6
33
 6
35
 6
other values
105

follow_up_Wechsler_Memory_ScaleIII_WMS_III

76%
31
 9
37
 7
36
 6
39
 6
other values
102

follow_up_Weight_kg

 22%
60
 6
65
 4
68
 4
55
 3
other values
 21

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