Zhang_2015_rheumatoid_arthritis

Study: The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

Publication: Zhang et al., The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment (2015, Nature Medicine)

External link: SPIRE database (MAGs, genes and proteins including annotations)

Study accession: PRJEB6997

Last annotation change: 2025-09-30

Human Metadata

Anti-AKA_(Anti-keratin_antibody)

 29%
0
 148

Anti-APF_(Anti-perinuclear_factor)

 27%
0
 135
Weak +
 1

Anti-CCP_(Anti-citrullinated_protein_antibody,U/ml)

 40%
<25
 35
3200
 15
>3200
 12
94
 5
other values
 136

CRP_mg_L

55%
1.2
 5
0.52
 3
0.59
 3
0.62
 3
other values
262

CRP_mg_dl

55%
0.12
 5
0.66
 3
1.196
 3
1.224
 3
other values
262

Change_of_prescription

 0%
Taking Methotrexate for 1month, then taking Methotrexate
 2
Taking Methotrexate, pred+etanercept for 5 months, then taking Methotrexate, Hydroxychloroquine, etanercept
 1
Taking for 6 months,then taking Methotrexate
 1

Cholesterol_mg_dl

51%
131.154
 6
137.308
 6
158.077
 6
170.769
 6
other values
 232

Cholesterol_mmol_L

51%
3.41
 6
3.57
 6
4.11
 6
4.44
 6
other values
 232

Creatinine_mg_dl

75%
0.531674
 28
0.576923
 27
0.497738
 16
0.542986
 16
other values
287

Creatinine_umol_L

75%
47
 28
51
 27
44
 16
48
 16
other values
287

Erythrocyte_sedimentation_rate

55%
44
 14
10
 12
23
 12
17
 10
other values
 229

GPT_ALT

75%
13
 35
14
 29
11
 28
20
 19
other values
266

Glucose_mg_dl

 27%
88.2883
 22
91.8919
 16
93.6937
 13
100.901
 10
other values
 73

Glucose_mmol_L

 27%
4.9
 22
5.1
 16
5.2
 13
5.6
 10
other values
 73

HDL_mg_dl

 22%
32.6923
 5
33.8462
 5
36.5385
 4
37.6923
 4
other values
 94

HDL_mmol_L

 22%
0.85
 5
0.88
 5
0.95
 4
0.98
 4
other values
 94

Hemoglobin_g_L

77%
130
 20
122
 16
134
 16
125
 15
other values
318

IgA_(Immunoglobulin_A,g/L)

 39%
1.84
 7
2.64
 5
3.95
 5
4.34
 5
other values
 175

IgG_(Immunoglobulin_G,g/L)

 41%
14
 9
16.8
 7
11.9
 6
17.2
 6
other values
 178

IgM_(Immunoglobulin_M,g/L)

 39%
0.85
 7
1.16
 7
0.95
 6
1.3
 5
other values
 171

LDL_mg_dl

 24%
87.3077
 5
106.154
 4
105
 3
108.462
 3
other values
 105

LDL_mmol_L

 24%
2.27
 5
2.76
 4
1.21
 3
1.75
 3
other values
 105

Leukocytes

77%
6.34
 7
7.21
 7
5.11
 6
5.4
 6
other values
359

Plateleta

77%
190
 9
260
 8
306
 8
247
 7
other values
353

RF_(Rheumatoid_factor,U/ml)

54%
<10.4
 31
<10.1
 21
113
 4
109
 3
other values
 210

Treatment_duration

 20%
3M
 86
6M
 11
1M
 3
16M
 2
other values
 2

Triglycerides_mg_dl

51%
66.6667
 9
88.5965
 8
100.877
 7
77.193
 7
other values
 223

Triglycerides_mmol_L

51%
0.76
 9
1.01
 8
0.88
 7
0.94
 7
other values
 223

methotrexate

100%
n
426
Y
 71

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Sample alias Spire sample name Longitude Latitude Geographic location Location resolution Collection date Collection date end Last change Tax id Environment material Environment biome Environmental package Environment feature Artificial Pmid Doi