Larson_2022_elderly

Study: Instability, Heterogeneity, and Pathogenicity Reservoirs in the Skin, Oral, and Gut Microbiota of Older Adults

Publication: Larson et al., Associations of the skin, oral and gut microbiome with aging, frailty and infection risk reservoirs in older adults (2022, Nature Aging)

External link: SPIRE database (MAGs, genes and proteins including annotations)

Study accession: PRJNA699281

Last annotation change: 2025-10-31

Human Metadata

location

100%
USA (country)
1350

resolution of location info

100%
country
1350

source material

100%
saliva material [ENVO:02000036]
 132
skin of back [UBERON:0001068]
 132
skin of elbow [UBERON:0001517]
 132
skin of knee [UBERON:0001510]
 132
other values
822

source material environment

100%
skin environment [ENVO:2100003]
919
mouth environment [ENVO:08000002]
 132
nasopharynx [UBERON:0001728]
 131
intestine environment [ENVO:2100002]
 120
other values
 48

days since first sample

100%
0
 503
14
 424
28
 423

sex

96%
female
954
male
 348

age (years)

96%
65.0-71.0
 326
73.0-77.0
 263
79.0-82.0
 260
85.0-88.0
 249
89.0-97.0
 204

age category

96%
adult
1302

weight (kg)

96%
45.1-59.0
 338
59.9-64.0
 207
64.4-76.7
 244
77.1-93.0
 304
95.3-140.6
 209

body mass index

96%
17.1-22.6
 261
22.7-25.1
 275
25.2-26.9
 267
27.3-30.1
 263
32.2-62.6
 236

height (cm)

96%
147.3-153.7
 270
154.9-158.8
 263
160.0-162.6
 305
165.1-175.3
 216
176.5-188.0
 248

disease status

96%
COHORT
1302

medication

 32%
Aspirin
 29
ATC J01; Tamsulosin
 10
Acetaminophen; Albuterol; Alprazolam; ATC A02A; Atorvastatin; Azithromycin; Bisacodyl; Calcium carbonate; Cetylpyridinium; Chlorhexidine; Docusate; Duloxetine; Fluticasone propionate; Furosemide; Guaifenesin; Hypromellose; Insulin detemir; Insulin lispro; Ipratropium; Lactobacillus acidophilus; Lidocaine; Loperamide; Magnesium oxide; Mesalamine; Metoprolol; Mirabegron; Ondansetron; Oxycodone; Pantoprazole; Polyethylene glycol 3350; Potassium chloride; Pregabalin; Ranitidine; Ropinirole; Senna; Simethicone; Sodium chloride; Sucralfate; Trazodone; Vilanterol
 10
Acetaminophen; Albuterol; Aspirin; Bisacodyl; Brimonidine; Calcium carbonate; Carboxymethylcellulose sodium; Clopidogrel; Fluticasone propionate; Gabapentin; Glucagon hydrochloride; Hypromellose; Latanoprost; Lidocaine; Magnesia, [milk of]; Montelukast; Omeprazole; Ondansetron; Oxycodone; Senna; Simvastatin; Sodium phosphate; Timolol
 10
other values
 376

time series data available?

100%
yes
1292
no
 58

time series: count of timepoints

100%
3
1271
1
 58
2
 21

time series: length in days

100%
28
1292
0
 58

...73

 0%
Homeopathic medicine
 10

.Allergies

 33%
Yes
 268
No
 187

A.Rockwood.Frailty.index.score.of.equal.to.or.greater.than.0.5.to.avoid.extremely.frail.individuals.

 33%
No
 455

AE.1.Did.the.patient.have.an.Adverse.Event.during.this.study

83%
No
1120
Yes
 10

AE.2.What.was.the.severity.of.the.event

 0%
Mild
 10

AE.3.Study.Intervention.Relationship

 0%
Not Related
 10

AE.5.What.was.the.OUTCOME.of.the.Adverse.Event.

 0%
AE Still Present, Being Treated
 10

AE.6..Was.this.Adverse.Event.Expected.

 0%
No
 10

AE.7..Was.this.Adverse.Event.Serious.

 0%
Yes
 10

Additional.Comments.

 0%
Subject has had significant mental decline since last visit.
 9

Allergies..Please.explain

 19%
seasonal
 29
Bactrim, tetanus + toxoid
 10
Boniva, Fosamax, namenda
 10
Ceftriaxone, Ciprofolxacin, Rocephin
 10
other values
 209

Angina

 33%
No
 455

Antibacterial_soap

 33%
Yes
 266
No
 169
Unknown
 20

Antibiotic_range

 4%
43497
 10
44335
 10
9/14 to 9/28, first sampling at 9/29
 10
April
 10
other values
 20

Antibiotics_or_antivirals

 33%
No
 455

Antimicrobial.Use.....Oral.antibiotics..antifungals.in.the.past.6.months.or.topical.within.the.last.2.weeks

 33%
No
 345
Yes
 90
Unknown
 20

Antimicrobial.Use...Please.explain...47

 6%
antibiotic
 50
Lamasil
 10
Ciprofloxacin
 10
Baza cream antifungal
 10
Azithromycin 500mg unknown reason
 10

Anxiety

 33%
No
 395
Yes
 60

Arrhythmia,_chronic_atrial_fibrillation,_sick_sinus_syndrome

 33%
No
 386
Yes
 69

Asthma

 33%
No
 395
Yes
 60

Beans_consumption_frequency_not_including_green_beans

 41%
1 time last month
 127
1 time per week
 119
2 times per week
 100
Never
 80
other values
 130

Bipolar_Mood_Disorder

 33%
No
 445
Yes
 10

CARETAKING....11a..Over.the.past.7.days..how.many.days.did.you.perform.any.caring.for.another.person.such.as.children..dependent..spouse.or.another.adult.

 33%
Never
 335
Seldom (1-2 days)
 50
Often (5-7days)
 50
Sometimes (3-4 days)
 20

CARETAKING....11b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.caretaking.

 8%
1-20 minutes
 40
2-4 hours
 20
more than 8 hours
 20
1 hour but less than 2 hours
 10
other values
 30

COGNITION..Total

 33%
0
 387
1
 40
0.5
 28

CONTINENCE...Bladder

 33%
Continent (0)
 289
Incontinent (1)
 157
Unknown (-1)
 9

CONTINENCE...Bladder.Catheter

 33%
No
 446

CONTINENCE...Bowel

 33%
Continent (0)
 388
Incontinent (1)
 58
Unknown (-1)
 9

CONTINENCE...Bowel.Constipated

 33%
No
 446

CONTINENCE..Total

 33%
0
 289
1
 99
2
 58
-2
 9

COPD

 33%
No
 366
Yes
 89

Cancer...select.all.that.apply..choice.Other.

 33%
No
 415
squamous cell carcinoma
 10
papillary thyroid carcinoma
 10
basal cell skin cancer
 10
Skin cancer
 10

Cardio_Illness_Other

 33%
No
 407
chronic ischemic heart disease
 19
cardiomyopathy
 10
aortic aneurysm
 10
Atherosclerotic heart disease without angina
 9

Cerebral_Palsy

 33%
No
 455

Cerebrovascular_stroke,_TIA

 33%
No
 405
Yes
 50

Chronic.Illness....ENDOCRINE

 33%
No (0)
 336
Diabetes mellitus (with or without complication) (1)
 119

Chronic.Illness...CARDIAC

 33%
No (0)
 298
Yes (1)
 118
Two or more cardiac illnesses selected below (2)
 39

Chronic.Illness..Total.Score

 33%
2
 100
1
 80
0
 68
4
 59
other values
 148

Chronic_renal_failure

 33%
No
 435
Yes
 20

Clinical.Frailty.Scale

 31%
Very Fit
 139
Severely Frail
 89
Moderately Frail
 88
Well
 59
other values
 50

Cognition

 33%
WNL (0)
 387
Dementia (1)
 40
CIND (.5)
 28

Comment

 0%
did not continue due to antibiotics
 10
subject was getting surgery on toe 5/22, would be given antibiotic
 1
Subject started antibiotics for UTI on 4/11/19
 1

Comorbidities

 27%
Arrhythmia, Hypertension, Cerebrovascular, Chronic renal failure, hemiplegia
 10
Arrhythmia, valvular
 10
CEREBROVASCULAR, ANXIETY AND DEPRESSION
 10
Peripheral vascular
 10
other values
 336

Comorbidities..e.g...diabetes.

 33%
Yes
 396
No
 59

Complete..10

 33%
Complete
 455

Complete..11

 33%
Complete
 455

Complete..6

 33%
Complete
 455

Complete..7

 28%
Complete
 383

Complete..8

 49%
Complete
 644
Incomplete
 19

Complete..9

90%
Complete
1140
Incomplete
 82

Concomitant.Medication.Use..during.study.duration.

 33%
Yes
 445

Congestive_heart_failure

 33%
No
 415
Yes
 40

Consumption_fruits_frequency

 47%
2-5 times
 233
Never
 174
Daily
 159
Once
 78

Consumption_of_candy_including_chocolate_frequency_in_the_past_month_not_including_sugar_free_candy

 41%
1 time per week
 139
1 time per day
 80
2-3 times last month
 80
3-4 times per week
 80
other values
 177

Consumption_of_cheese_frequency_in_the_past_month_not_including_cheese_on_pizza

 41%
1 time per day
 199
3-4 times per week
 130
2 times per week
 109
2-3 times last month
 40
other values
 78

Consumption_of_dessert_sweets_soda_or_juice_frequency

 47%
Daily
 409
2-5 times
 166
Never
 30
Once
 29

Consumption_of_frozen_sweets_such_as_ice_cream_frequency_in_the_past_month_not_including_sugar_free_kinds

 41%
3-4 times per week
 99
2 times per week
 90
2-3 times last month
 90
Never
 77
other values
 200

Consumption_of_other_vegetables_frequency

 41%
1 time per day
 169
3-4 times per week
 150
5-6 times per week
 68
1 time per week
 60
other values
 109

Consumption_of_popcorn_frequency_in_the_past_month

 41%
Never
 297
1 time last month
 130
2-3 times last month
 50
1 time per week
 49
other values
 30

Consumption_of_processed_meat_frequency_in_the_past_month

 41%
1 time per day
 228
3-4 times per week
 89
Never
 80
1 time per week
 50
other values
 109

Consumption_of_red_meat_frequency_in_the_past_month

 41%
2 times per week
 189
2-3 times last month
 158
1 time per week
 79
3-4 times per week
 70
other values
 60

Consumption_of_vegetables_frequency

 47%
Never
 243
2-5 times
 205
Daily
 137
Once
 49

Consumption_of_whole_grains_frequency

 47%
Daily
 306
2-5 times
 152
Never
 146
Once
 40

Consumption_red_meat_frequency

 47%
2-5 times
 273
Never
 195
Once
 156
Daily
 20

Cooked_grains_consumption_frequency_not_including_white_rice

 41%
Never
 308
2-3 times last month
 69
1 time per week
 50
1 time last month
 49
other values
 80

Date.of.Visit.1

 25%
2019-04-10T00:00:00Z
 40
2018-04-27T00:00:00Z
 30
2018-04-11T00:00:00Z
 20
2019-04-30T00:00:00Z
 20
other values
 235

Dematologic.condition.skin.site

 2%
nose
 10
BILATERAL FACIAL WARTS
 10
Abdominal folds
 10

Dementia

 33%
No
 405
Yes
 50

Dentures_in_the_past

 47%
Yes
 333
No
 311

Depression

 33%
No
 357
Yes
 98

Dermatologic.conditions

 33%
No
 367
Yes
 78

Dermatologic.conditions.status

 5%
Current
 48
Resolved
 20

Dermatologic_conditions

 5%
Candida
 10
FACIAL WARTS
 10
HX of Psoriasis
 10
Rosacea
 10
other values
 28

Do.you.have.pain..

 33%
No
 347
Yes
 108

Dominant.Hand

 33%
Right
 435
Left
 20

During.the.past.month..how.often.did.you.eat.doughnuts..sweet.rolls..danish..muffins..pan.dulce..or.pop

 41%
Never
 129
2 times per week
 110
2-3 times last month
 99
3-4 times per week
 68
other values
 150

During_the_past_month_how.often.did.you.eat.hot.or.cold.cereals..Mark.one.

 41%
1 time per day
 149
2 times per week
 90
1 time per week
 80
2-3 times last month
 68
other values
 169

Elbow_pain_in_both_arms

 33%
No
 445
Yes
 10

Elbow_pain_in_the_left_arm

 33%
No
 455

Elbow_pain_in_the_right_arm

 33%
No
 445
Yes
 10

End_date_of_status_infection

 1%
2018-03-12T00:00:00Z
 10
2018-02-23T00:00:00Z
 10

Endocrine..Other

 5%
hypothyroidism
 38
hypothyroid
 10
graves disease, had thyroidectomy
 10
Not diabetes, other =Hypothyroidism
 10

Event.Name

90%
Visit 1-Baseline
 455
Visit 2
 384
Visit 3
 383

FRAILTY.SCALE.sub.Score

 33%
0
 110
2
 68
1
 30
45057
 30
other values
 217

FUNCTION...Bathing

 33%
Independent (0)
 268
Assisted (.5)
 158
Depdendent / Non-Ambulate (1)
 29

FUNCTION...Dressing

 33%
Independent (0)
 357
Assisted (.5)
 78
Depdendent / Non-Ambulate (1)
 20

FUNCTION...Eating

 33%
Independent (0)
 435
Assisted (.5)
 20

FUNCTION...Finances

 33%
Independent (0)
 228
Depdendent / Non-Ambulate (1)
 207
Assisted (.5)
 20

FUNCTION...Meds

 33%
Independent (0)
 238
Assisted (.5)
 217

FUNCTION...Toileting

 33%
Independent (0)
 356
Assisted (.5)
 69
Depdendent / Non-Ambulate (1)
 30

FUNCTION..Total

 33%
0
 228
2
 79
3
 58
45047
 30
other values
 60

Fatigue

 33%
No
 329
Yes
 116

Forarm_pain_in_both_arms

 33%
No
 455

Forarm_pain_the_in_the_left_arm

 33%
No
 455

Forarm_pain_the_right_arm

 33%
No
 455

Frailty.Index....Total.Frailty.Score...Total.Score..39..

 33%
512820510000000
 98
0
 30
0.435897436
 29
0.153846154
 20
other values
 278

Frailty.Index..Conducted

 32%
Yes
 435

Frequency_of_brushing_teeth

 47%
More than once a day
 520
Less than once a day
 115

Frequency_of_teeth_brushing

 41%
More than once a day
 496
Less than once a day
 60

Frequency_of_tobacco_usage

 47%
No
 634
Yes
 10

Fried_potatoes_consumption_frequency

 41%
Never
 287
2-3 times last month
 90
1 time per week
 60
2 times per week
 50
other values
 69

Fruit_consumption_frequency

 41%
1 time per day
 228
2 or more times per day
 169
3-4 times per week
 50
1 time per week
 30
other values
 79

Full_list_of_medication_and_vitamins_taken

 33%
Aranesp, calcitriol, Liquacel, Midorine HCL, Renvela, Konex, Omeprazole, Aspirin, Nephro-vite, Gavilax, cal-gest, cyclosporine, lamotrigine, mycophenolate mofetil, Artificial tears, gabapentin, pravastatin, bisac-evac, acetaminophen, acetaminophen suppository.
 10
Atorvastatin, escitalopram, lorazepam, lisinopril, androgel, vitamin B3, Vitamin B12, Aspirin
 10
Avodart, Diovan, Mybertriq, rapaflo, viibryd, Xanax, Vitamin C, Vitamin B3, Colace, ferrous gluconate, niacinanide, psyllium
 10
Carbidopa-Levodopa
 10
other values
 405

GARDENING.....10b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.outdoor.gardening.

 11%
41-59 minutes
 40
1-20 minutes
 39
1 hour but less than 2 hours
 30
21-40 minutes
 20
other values
 20

GARDENING....10a..Over.the.past.7.days..how.many.days.did.you.perform.any.outdoor.gardening.

 33%
Never
 306
Seldom (1-2 days)
 89
Sometimes (3-4 days)
 30
Often (5-7days)
 30

GERD

 33%
No
 337
Yes
 118

HEAVY.HOUSEWORK....7a..Over.the.past.7.days..how.many.days.did.you.perform.any.heavy.housework.such.as.vacuuming..scrubbing.floors..washing.windows.or.carrying.wood.

 33%
Never
 327
Seldom (1-2 days)
 98
Sometimes (3-4 days)
 20
Often (5-7days)
 10

HEAVY.HOUSEWORK....7b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.heavy.housework..

 8%
1-20 minutes
 40
21-40 minutes
 30
2-4 hours
 29
1 hour but less than 2 hours
 19

HOME.REPAIRS....8a..Over.the.past.7.days..how.many.days.did.you.perform.any.home.repairs.like.painting..wallpapering..electrical.work..etc.

 33%
Never
 405
Often (5-7days)
 30
Seldom (1-2 days)
 10

HOME.REPAIRS....8b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.home.repairs..

 3%
1 hour but less than 2 hours
 30
21-40 minutes
 10
1-20 minutes
 10

Hand_pain_in_both_hands

 33%
No
 425
Yes
 30

Hand_pain_in_the_right_hand

 33%
No
 445
Yes
 10

Hand_pain_the_left_hand

 33%
No
 426
Yes
 29

Have.you.had.tooth.or.gum.pain.or.bleeding

 47%
No
 527
Yes
 117

Have.you.used.mouthwash.demonstrated.to.have.antimicrobial.effects..e.g...Listerine.

 47%
Yes
 420
No
 214

Hemiplegia,_Paraplegia,_Quadriplegia

 33%
No
 425
Yes
 30

Hepatic_Cirrhosis

 33%
No
 455

How.many.prescription.medications.is.the.patient.taking.on.a.regular.basis..

 33%
0-4 (0)
 208
8-13 (1)
 99
>=14 Prescriptions (2)
 79
5-7 (.5)
 69

Hyperlipidemia

 33%
No
 276
Yes
 179

Hypertension

 33%
Yes
 257
No
 198

If.resolved..please.provide.start.and.end.date

 2%
fluorouracil cream stopped 2/15/2019
 10
April
 10
9/2018 - 3/2019
 9

If.topical..please.indicate.skin.site...74

 3%
unknown site of dermasarra lotion application.
 10
unknown body site
 10
triamcinolone acetonide cream- apply topically to any area of puritis on body every 4 hours as needed.
 10
?
 10

If.topical..please.indicate.skin.site.used

 1%
Possible antimicrobial use in March, just over 6 months prior to presentation.
 10
Abdominal folds (not sampled in study)
 10

Immunologic_conditions

 0%
osteo arthritis
 10

Inflammatory_Bowel_Disease:_Crohns_Ulcerative_Colitis

 33%
No
 425
Yes
 30

Is.the.participant.65.or.older

 33%
Yes
 445

LAWN.WORK....9a..Over.the.past.7.days..how.many.days.did.you.perform.any.lawn.work.or.yard.care.such.as.snow.removal..wood.chopping..etc.

 33%
Never
 346
Seldom (1-2 days)
 99
Often (5-7days)
 10

LAWN.WORK....9b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.lawn.work.or.yard.care..

 8%
2-4 hours
 69
1 hour but less than 2 hours
 40

LIGHT.HOUSEWORK....6a..Over.the.past.7.days..how.many.days.did.you.perform.any.light.housework.such.as.dusting.or.washing.dishes.

 33%
Often (5-7days)
 199
Never
 148
Seldom (1-2 days)
 69
Sometimes (3-4 days)
 39

LIGHT.HOUSEWORK....6b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.light.housework..

 22%
1-20 minutes
 148
21-40 minutes
 80
1 hour but less than 2 hours
 59
41-59 minutes
 10

LIGHT.SPORTS.RECREATION....2a..Over.the.past.7.days..how.often.did.you.participate.in.Light.Sports.or.Recreational.activities.such.as.bowling..golf.with.a.cart..shuffleboard..fishing.from.a.boat.or.pier.or.other.similar.activities.

 33%
Never
 326
Seldom (1-2 days)
 69
Often (5-7days)
 40
Sometimes (3-4 days)
 20

LIGHT.SPORTS.RECREATION....2b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.these.light.sport.or.recreational.activities..

 8%
1-20 minutes
 50
41-59 minutes
 39
21-40 minutes
 10
2-4 hours
 10
1 hour but less than 2 hours
 10

Left.Hand.Grip.Strength...245

 33%
20
 50
15
 40
16
 30
18
 30
other values
 295

Left.Hand.Grip.Strength...246

 33%
14
 59
20
 50
18
 40
8
 28
other values
 268

Left.Hand.Grip.Strength..1

 33%
16
 70
20
 40
15
 30
22
 30
other values
 275

Length.of.Residence.in.Facility

 16%
Greater than 6 Months
 207
Less than 6 Months
 10

Leukaemia

 33%
No
 455

Lymphoma

 33%
No
 455

MOBILITY...Aid

 33%
No (0)
 247
Yes (1)
 208

MOBILITY...Ambulates

 33%
Independent (0)
 365
Assisted (.5)
 70
Depdendent / Non-Ambulate (1)
 20

MOBILITY...Balance

 33%
WNL-Independent (0)
 326
Impaired-Assisted / Dependent (1)
 129

MOBILITY...History.of.Falls

 33%
No (0)
 248
Yes (1)
 198
Unknown (-1)
 9

MOBILITY...Transfer

 33%
Independent (0)
 346
Assisted (.5)
 79
Depdendent (1)
 30

MOBILITY...Type.of.Aid

 15%
4 WW
 99
Wheelchair
 79
Unknown
 10
Cane
 10
2 WW
 10

MOBILITY..Total

 33%
0
 208
45049
 50
1
 49
2
 49
other values
 99

MODERATE.SPORTS.RECREATION....3a..Over.the.past.7.days..how.often.did.you.participate.in.Moderate.Sports.or.Recreational.activities.such.doubles.tennis..ballroom.dancing..hunting..ice.skating..golf.without.a.cart..softball.or.other.similar.activities.

 33%
Never
 417
Often (5-7days)
 19
Seldom (1-2 days)
 10
Sometimes (3-4 days)
 9

MODERATE.SPORTS.RECREATION....3b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.these.moderate.sport.or.recreational.activities..

 2%
2-4 hours
 18
41-59 minutes
 10
1 hour but less than 2 hours
 10

MOOD..Total

 33%
0
 335
1
 80
2
 20
45047
 10
0.5
 10

MUSCLE.STRENGTH.AND.ENDURANCE....5a..Over.the.past.7.days..how.many.days.did.you.do.any.exercises.specifically.to.increase.muscle.strength.and.endurance.such.as.lifting.weights..pushups..etc...

 33%
Never
 247
Sometimes (3-4 days)
 99
Seldom (1-2 days)
 80
Often (5-7days)
 19

MUSCLE.STRENGTH.AND.ENDURANCE....5b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.exercises.to.increase.muscle.strength.and.endurance.

 15%
1-20 minutes
 109
21-40 minutes
 40
1 hour but less than 2 hours
 30
41-59 minutes
 29

Medication_stauts

 29%
Current
 357
Resolved
 39

Mental_health_diagnosis

 33%
No
 327
Yes
 128

Metastatic_Solid_Tumor

 33%
No
 435
Yes
 20

Mexican_food_frequency_in_the_past_month

 41%
Never
 370
1 time last month
 86
2-3 times last month
 50
2 times per week
 30
1 time per day
 20

Mixed_Connective_Tissue_Disease

 33%
No
 455

Mood.1

 33%
WNL (0)
 345
Depression (1)
 90
Low Mood (.5)
 20

Mood.2

 3%
Psychosis / Mania / Anxiety (1)
 40

NUTRITION...Weight

 33%
Stable (0)
 345
Gain (.5)
 60
Loss (1)
 50

NUTRITION..Appetite

 33%
WNL
 437
Unknown
 9
Poor
 9

NUTRITION.TOTAL

 33%
0
 345
0.5
 60
1
 50

Nephrotic_syndrome

 33%
No
 455

OTHER.Pain

 7%
Both feet hurt from diabetes neuropathy
 10
Hand pain is occasional from arthritis but well controlled
 10
Left shoulder pain, sometimes travels down arm
 10
Sometimes knees and back hurt from arthritis
 10
other values
 58

On_average_how_many_hours_or_minutes_did_you_spend_on_walking_outside_over_the_past_week

 22%
1-20 minutes
 88
1 hour but less than 2 hours
 80
21-40 minutes
 70
41-59 minutes
 50
other values
 19

Other_chronic_illnesses

 3%
osteoporosis
 20
alcoholism
 10
Heart Transplant
 10
Osteoarthritis
 9

Other_gastrointestinal_illnesses

 33%
No
 436
gluten intolerance
 10
Diverticulitis
 9

Other_kinds_of_potatoes_consumption

 41%
1 time per week
 148
2-3 times last month
 128
3-4 times per week
 90
2 times per week
 80
other values
 110

Other_mental_health_issues

 33%
No
 445
Adjustment disorder
 10

Other_neuromuscular_illnesses

 33%
No
 415
encephalopathy unspecified
 10
encephalopathy
 10
Myotonil muscular dystrophy
 10
Alzheimer disease
 10

Other_pulmonary_illnesses

 33%
No
 425
OSA
 20
Chronic respiratory failure
 10

Other_vascular_illnesses

 33%
No
 425
venous insufficiency (chronic)
 10
Pulmonary hypertension
 10
CAO
 10

Over_the_past_week,_how_many_days_did_you_go_on_a_walk_outside_your_home

 33%
Often (5-7days)
 208
Never
 138
Seldom (1-2 days)
 60
Sometimes (3-4 days)
 49

Parkinsons

 33%
No
 416
Yes
 39

Peptic_Ulcer

 33%
No
 455

Peripheral_vascular_illness

 33%
No
 405
Yes
 50

Pizza_consumption_frequency_in_the_past_month

 41%
2-3 times last month
 238
1 time per week
 130
1 time last month
 118
Never
 70

Presence.of.visible.skin.or.oral.lesions.at.site.of.planned.sampling

 33%
No
 455

Previous_MI

 33%
No
 426
Yes
 29

Primary.reason.for.terminating.participation.in.the.study

 28%
completed study
 371
In the Investigator's opinion, it was not in the Participant's best interest to continue.
 10
Other
 2

Prior.medication.use..within.6.months.before.the.study.

 33%
Yes
 426
No
 29

Prior_medication

 16%
see list
 20
Atorvastatin, escitalopram, lorazepam, lisinopril, androgel, Aspirin
 10
Avodart, Diovan, Mybertriq, rapaflo, viibryd, Xanax, Colace, ferrous gluconate, niacinamide, laxatives
 10
Carbidopa, Levodopa
 10
other values
 168

Psychotic_Illness

 33%
No
 455

Pure_fruit_juice_frequency

 41%
1 time per day
 210
Never
 150
3-4 times per week
 80
2 times per week
 47
other values
 69

Regular_soda_frequency

 41%
Never
 449
1 time last month
 50
1 time per week
 27
1 time per day
 10
other values
 20

Repeat.Instance

90%
0
1222

Right.Hand.Grip.Strength...247

 33%
18
 50
14
 49
16
 40
20
 30
other values
 276

Right.Hand.Grip.Strength...248

 33%
20
 50
14
 48
16
 40
18
 40
other values
 267

Right.Hand.Grip.Strength...249

 33%
22
 40
14
 39
12
 30
18
 30
other values
 306

SENSORY..Hearing

 33%
WNL (0)
 347
Impaired (1)
 108

SENSORY..Speech

 33%
WNL (0)
 435
Impaired (1)
 20

SENSORY..Total

 33%
0
 308
1
 118
2
 19
3
 10

SENSORY..Vision

 33%
WNL (0)
 397
Impaired (1)
 58

SKIN..Edema

 33%
No (0)
 357
Yes (1)
 98

SKIN..Total

 33%
0
 357
1
 88
2
 10

SKIN..Ulcers

 33%
No (0)
 445
Yes (1)
 10

STRENUOUS..SPORTS.RECREATION....4a..Over.the.past.7.days..how.often.did.you.participate.in.strenuous.Sports.or.Recreational.activities.such.as.jogging..swimming..cycling..singles.tennis..aerobic.dance..skiing..downhill.cross.country..or.other.similar.activities.

 33%
Never
 385
Seldom (1-2 days)
 40
Sometimes (3-4 days)
 20
Often (5-7days)
 10

STRENUOUS.SPORTS.RECREATION....4b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.these.strenuous.sport.or.recreational.activities..

 5%
2-4 hours
 20
1-20 minutes
 20
1 hour but less than 2 hours
 20
21-40 minutes
 10

Salad_consumption_frequency

 41%
3-4 times per week
 130
1 time per day
 129
5-6 times per week
 80
1 time per week
 79
other values
 138

Seizure_Disorder

 33%
No
 435
Yes
 20

Self.Reported.gastrointestinal.distress..diarrhea.episode.2.or.more.on.the.same.day.in.the.last.month.and.any.intestinal.bleeding.in.the.last.month.

 33%
No
 455

Setting.

 33%
3
 445
2
 10

Solid_Tumor

 33%
No
 445
Yes
 10

Spinal_Cord_injury

 33%
No
 455

Status_immunologic_conditions

 0%
Current
 10

Status_of_infection

 3%
Resolved
 50

Sweetened_fruit_drinks_or_energy_drinks_frequency

 41%
Never
 398
2-3 times last month
 60
1 time last month
 38
1 time per day
 20
other values
 40

Sweetened_or_non_sweetened_coffee_and_tea_frequency,_artificially_sweetened_not_included

 41%
Never
 339
1 time per day
 50
2 times per week
 48
5-6 times per week
 39
other values
 80

Systemic_Lupus_Erythematosus

 33%
No
 455

Systemic_or_local_infections

 4%
C.Diff
 10
GI and respiratory infection
 10
MRSA
 10
Pneumonia and flu last winter
 10
other values
 20

Terminal_illness

 33%
No
 445
Yes
 10

Time_of_foot_walk

81%
3.75
 60
4.28
 60
17.72
 30
2.68
 30
other values
917

Time_of_last_brush

 37%
8
 139
7
 120
0.27083333333333331
 50
10
 50
other values
 140

Time_of_last_brush_AM_or_PM

 37%
AM
 419
PM
 80

Tobacco_usage

 41%
No
 556

Tomato_sauce_consumption_in_the_past_month_not_including_pizza_sauce

 41%
1 time per week
 180
2-3 times last month
 179
2 times per week
 90
Never
 40
other values
 67

Tooth_or_gum_bleeding

 41%
No
 516
Yes
 40

Total.Frailty.Score....Chronic.Illness.Score...Medication.Score...Frailty.Scale.SubScore

 33%
2
 98
0
 30
17
 29
1
 20
other values
 278

Type.of.Dementia

 2%
vascular dementia without behavioral disturbance
 10
vascular
 10
Primary unspecified without behavioral disturbance
 10

Type.of.Visit

 33%
Baseline
 435
Additional Sample
 20

Type_of_milk

 32%
1% 1/2% or low fat milk
 130
Whole or regular milk 2%
 90
Fat Free Skim or Non Fat Milk
 60
almond milk
 50
other values
 109

Unintentional_weight_loss_of_10_pounds_in_the_last_year

 33%
No
 396
Yes
 59

Usage_of_antimicrobial_mouthwash

 41%
No
 366
Yes
 190

Valvular,_prosthetic_aortic_or_mitral_valves

 33%
No
 425
Yes
 30

Visit.Time.Point

 33%
Visit 1 (Day 0)
 455

Visit.Time.Point.1

 33%
Visit 1 (Day 0)
 455

Visit.Time.Point.2

 33%
Visit 1 (Day 0)
 455

Visit.Type

 33%
Baseline
 435
Additional Sample
 10

WORK....12a..Over.the.past.7.days..how.many.days.did.you.perform.any.work.for.pay.or.as.a.volunteer.

 33%
Never
 207
Seldom (1-2 days)
 138
Often (5-7days)
 70
Sometimes (3-4 days)
 40

WORK....12b..On.average..how.many.hours.minutes.per.day.did.you.engage.in.work.

 18%
2-4 hours
 69
1 hour but less than 2 hours
 40
21-40 minutes
 39
1-20 minutes
 30
other values
 70

WORK....12c..Which.of.the.following.categories.best.described.the.amount.of.physical.activity.required.on.your.job.and.or.volunteer.work.

 18%
Mainly sitting with slight arm movements
 128
Walking with some handling of materials < 50 lbs.
 60
Sitting or standing with some walking
 60

Was_Program_of_All-Inclusive_Care_for_the_Elderly_completed

 33%
Yes
 455

Was_foot_walk_completed

 33%
Yes
 385
Not Attempted
 70

What.time.do.you.last.brush.your.teeth

 32%
AM
 196
PM
 128
0.25
 49
am
 30
other values
 38

X..NOTE..Please.respond.appropriately....1..If.Dementia.has.been.selected.under.Neuro.Muscular.illnesses..enter.a.value.of..1....2..If.Dementia.was.NOT.selected.under.Neuro.Muscular.illnesses..enter.a.value.of.0.

 33%
0
 405
-1
 50

X..NOTE..Please.respond.appropriately....1..If.Peptic..Ulcer.is.the.ONLY.selected.Gastro.Intestinal..illness..enter.a.value.of..1.....2..If.Peptic..Ulcer.is.NOT.the.only.Gastro.Intestinal.illness.selected...OR..is.not.selected.at.all.....OR..NO.illnesses.were.selected..enter.a.value.of.0.

 33%
0
 455

X1..Do.you.feel.that.everything.you.did.was.an.effort

 33%
Rarely or none of the time (< 1 day)
 337
Most or all of the time (5-7 days)
 70
Some or a little of the time (1-2 days)
 28
Occasionally or a moderate amount of the time (3-4 days)
 20

X15.Foot.Walk.....Time..2

81%
4.03
 90
3.62
 60
3.66
 40
16.66
 30
other values
877

X2..Do.you.feel.that.you.could.not.get.going.

 33%
Rarely or none of the time (< 1 day)
 347
Some or a little of the time (1-2 days)
 59
Most or all of the time (5-7 days)
 39
Occasionally or a moderate amount of the time (3-4 days)
 10

X24..During.the.past.month..how.often.did.you.eat.any.processed.meat..such.as.bacon..lunch.meats..or.hot.dogs..Include.processed.meats.you.had.in.sandwiches..soups..pizza..casseroles..and.other.mixtures...Processed.meats.are.those.preserved.by.smoking..curing..or.salting..or.by.the.addition.of.preservatives..Examples.are..ham..bacon..pastrami..salami..sausages..bratwursts..frankfurters..hot.dogs..and.spam...

 41%
2-3 times last month
 168
1 time per week
 150
1 time last month
 99
Never
 79
other values
 60

X28..During.the.past.month..how.often.did.you.eat.cookies..cake..pie.or.brownies..Do.not.include.sugar.free.kinds.

 41%
1 time per day
 109
2 times per week
 100
3-4 times per week
 90
1 time last month
 70
other values
 187

X2d..If.topical..please.indicate.skin.site.used

 13%
hands
 137
hand washing
 20
hand
 20
hand wash
 10

X4..During.the.past.month..what.kind.of.cereal.did.you.usually.eat..Print.cereal.

 38%
oatmeal
 88
raisin bran
 80
Fiber one
 30
cold cereal
 30
other values
 288

X5..If.there.was.another.kind.of.cereal.that.you.usually.ate.during.the.past.month..what.kind.was.it..Print.cereal..if.none.leave.blank..

 16%
cheerios
 60
oatmeal
 20
steel cut oatmeal
 20
Cheerios
 10
other values
 108

X6..During.the.past.month..how.often.did.you.have.any.milk..either.to.drink.or.on.cereal...Include.regular.milks..chocolate.or.other.flavored.milks..lactose.free.milk..buttermilk..Please.do.not.include.soy.milk.or.small.amounts.of.milk.in.coffee.or.tea..Mark.one.

 41%
1 time per day
 167
Never (go to question 8)
 100
3-4 times per week
 70
1 time per week
 50
other values
 169

dentures

 41%
No
 476
Yes
 80

individual.eats.meals.at.or.from.home.5.or.more.days.of.the.week

 19%
No
 257

latitude_original

100%
41.73
1350

longitude_original

100%
-72.79
1350

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Sample alias Spire sample name Longitude Latitude Geographic location Location resolution Collection date Collection date end Last change Tax id Environment material Environment biome Environmental package Environment feature Artificial Pmid Doi